Moldovan Horatiu, Adrian Molnar, Victor Costache, Ecaterina Bontas
Chapter: Infective Endocarditis in Intravenous Drug Users: Surgical Treatment
Intravenous drug use is associated with infective endocarditis. Besides, it does appear that left-sided infective endocarditis is a feature of general population, whereas right-sided infective endocarditis is common in intravenous drug users. The most common etiology of right-sided infective endocarditis in intravenous drug users is Staphylococcus aureus in about 75% followed by streptococci, Gramnegative bacilli and fungi. In case of intravenous drug users with infective endocarditis, optimal treatment strategies lack a general consensus. Additionally, the best indication and timing of surgery are debatable. To overcome these problems, the early and complete surgical debridement of infected tissue together with microbial therapy assures a good prognosis in the long term.
Keywords: endocarditis, drug-associated endocarditis, intravenous drug abuser endocarditis, intravenous drug users, right heart endocarditis